Asymmetric Synthesis of Trifluoromethylphenyl Cyclopropanes Catalyzed by Chiral Metalloporphyrins

Abstract

The asymmetric addition of 2,2,2-trifluorodiazoethane to styrene derivatives to give optically active trifluoromethylphenyl cyclopropanes (ee values up to 69%) was carried out by using chiral iron and ruthenium porphyrins as homogeneous and heterogeneous catalysts.

Key words

2,2,2-trifluorodiazoethane - iron porphyrins - ruthenium porphyrins - optically active trifluoromethylphenyl cyclopropanes - iron porphyrin polymers

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