Development of Palladium-Catalyzed Cycloalkenylation and its Application to Natural Product Synthesis

Abstract

To solve the drawback (considerable decrease in yield on a large scale) of cycloalkenylation employing stoichiometric amounts of Pd(OAc)₂, a novel palladium-catalyzed cycloalkenylation has been developed. Stereoselective total syntheses of several bioactive terpenoids have been achieved by means of the above catalytic reaction.

Key words

cycloalkenylation - natural product - catalytic reaction - bioactive terpenoid

References

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