Recent Synthetic Applications of Chiral Aziridines
31 December 2000 (online)
Due to their ready availability in chiral form, and propensity to undergo regio- and stereoselective ring opening, aziridines have found widespread use in asymmetric synthesis. This review attempts to summarise the breadth of use of chiral aziridines in synthesis that has recently been reported. Particular emphasis is put on the effect of substituents on ring openings, rearrangements and use as chiral ligands and auxiliaries.
aziridine - asymmetric synthesis - ring opening - rearrangements - regioselectivity