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Stereospecific Syntheses of Michellamines A and C
31 December 2000 (online)
The total syntheses of two of the three dimeric naphthylisoquinoline michellamines - A and C - were achieved by Pd-catalyzed cross-coupling of the appropriate 6'-bromo- or 6'-boronic acid-substituted tetrabenzylated korupsensamine A and B derivatives under nonaqueous conditions, followed by deprotection of the octabenzylated products.
naphthylisoquinoline alkaloids - michellamines - korupensamines - atropdiasteromer - Suzuki hetero-biaryl coupling