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Synlett 1996; 1996(2): 167-168
DOI: 10.1055/s-1996-5344
DOI: 10.1055/s-1996-5344
letter
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Synthesis of 4-Borono-L-phenylalanine
Further Information
Publication History
Publication Date:
31 December 2000 (online)
An enantiospecific synthesis of 4-borono-L-phenylalanine (L-BPA) is presented. Using a new boronic acid protecting group, palladium-catalysed coupling of a protected iodo-phenylboronic derivative with a L-serine-derived partner forms the basis of this approach.
Borophenylalanine - organozinc - palladium cross-coupling - boroneutrotherapy