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Synthesis 1996; 1996(4): 423-445
DOI: 10.1055/s-1996-4250
DOI: 10.1055/s-1996-4250
review
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Synthesis of Radiopharmaceuticals via Organotin Intermediates
Further Information
Publication History
Publication Date:
31 December 2000 (online)
The basic concepts and uses of organotin intermediates in the rapidly growing domain of radiopharmaceutical chemistry are reviewed. Organotin intermediates can readily be prepared, and radiohalodestannylation is both efficient and site selective to give labeled products in good yields and high specific activities.
organotin intermediates - iododestannylation - radiohalogens - radiopharmaceuticals