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Synlett 1995; 1995(10): 1079-1080
DOI: 10.1055/s-1995-5175
DOI: 10.1055/s-1995-5175
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An Efficient, Safe and Convenient One-Step Synthesis of β-Phenethylamines via Reductive Amination Reactions Utilizing Ti(OiPr)4 and NaBH4
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Publication History
Publication Date:
31 December 2000 (online)
A simple, mild and high-yielding procedure for the synthesis of β-phenethylamines is reported using facile reductive aminations of benzyl aldehyde and ketones with titanium(IV) isopropoxide and sodium borohydride.
Benzyl Ketone/Aldehyde - Reductive Amination - Titanium(IV) Isopropoxide - Sodium Borohydride - β-phenethylamines