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Synlett 1995; 1995(10): 1079-1080
DOI: 10.1055/s-1995-5175
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An Efficient, Safe and Convenient One-Step Synthesis of β-Phenethylamines via Reductive Amination Reactions Utilizing Ti(OiPr)4 and NaBH4

Sukanta Bhattacharyya* , Arindam Chatterjee, John S. Williamson
  • *Vijoygarh College, Department of Chemistry, Calcutta - 700032, India
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Publication Date:
31 December 2000 (online)

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A simple, mild and high-yielding procedure for the synthesis of β-phenethylamines is reported using facile reductive aminations of benzyl aldehyde and ketones with titanium(IV) isopropoxide and sodium borohydride.

Benzyl Ketone/Aldehyde - Reductive Amination - Titanium(IV) Isopropoxide - Sodium Borohydride - β-phenethylamines

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