PDF herunterladen
Synthesis 1992; 1992(7): 605-617
DOI: 10.1055/s-1992-26174
review
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Practical and Useful Methods for the Enantioselective Reduction of Unsymmetrical Ketones

Vinod K. Singh*
  • *Department of Chemistry, Indian Institute of Technology, Kanpur-208016, India
Weitere Informationen

Publikationsverlauf

Publikationsdatum:
17. September 2002 (online)

 als PDF herunterladen  Lizenzen und Reprints Alle Artikel dieser Rubrik

Enantioselective reduction of unsymmetrical ketones to optically active alcohols is very important in organic synthesis. Catalytic methods have been developed for this process and have not been reviewed previously. In this article the recently developed oxazaborolidine catalyzed reduction along with other useful reagents will be discussed. 1. Introduction 2. Oxazaborolidines 3. B-3-pinanyl-9-borabicyclo[3.3.1]nonane 4. Chlorodiisopinocampheylborane 5. 2,5-Dimethylborolane 6. BINAL-H 7. BINAP-Ru Complex 8. Conclusion