The Stereo- and Regiocontrolled Phenylsulfonylmethylation of an Unfunctionalized Carbon Atom. A Protocol for an Indirect Remote C-Alkylation

Hugo J. Monteiro

doi:10.1055/s-1992-21558

Synlett 1992; 1992(12): 990-992
DOI: 10.1055/s-1992-21558

letter

© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

The Stereo- and Regiocontrolled Phenylsulfonylmethylation of an Unfunctionalized Carbon Atom. A Protocol for an Indirect Remote C-Alkylation

Hugo J. Monteiro^*

^*Departamento de Química, Universidade de Brasília, 70910 Brasília, DF, Brasil

Abstract

als PDF herunterladen Alle Artikel dieser Rubrik

A protocol for the indirect alkylation, via phenylsulfonylmethylation, of the unfunctionalized γ-carbon atom of a carboxylic acid chain was developed. The stereo- and the regiocontrol of the alkylation are secured by the use, as a key step, of an intramolecular carbenoid C-H insertion of an α-diazo-β-ketosulfone.

PDF (162 kb)