Download PDF
Synlett 1992; 1992(7): 539-546
DOI: 10.1055/s-1992-21409
account
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Nickel(0)-Mediated Intramolecular Cyclizations of Enynes, Dienynes, Bis-Dienes, and Diynes

Kohei Tamao* , Kenji Kobayashi, Yoshihiko Ito
  • *Department of Synthetic Chemistry, Faculty of Engineering, Kyoto University, Kyoto 606, Japan
Further Information

Publication History

Publication Date:
08 March 2002 (online)

 PDF Download  Permissions and Reprints All articles of this category

Nickel(0)-mediated intramolecular cyclizations of enynes and diynes with isocyanides, "silylenes", and hydrosilanes have been found to be useful methods for the one-step synthesis of polycyclic compounds with functional groups, The article describes the following cyclization reactions and the properties, reactivities and synthetic utilities of new ring systems thus obtained. 1. Introduction 2. Cyclization of 1,n-Enynes, Dienynes, and 1,n-Diynes with Isocyanides 3. Cyclization of 1,7-Diynes and Bis-Dienes with Hydrosilanes 4. Cyclization of 1,6-Diynes with "Silylenes" 5. Conclusion