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Synlett 1991; 1991(8): 569-570
DOI: 10.1055/s-1991-20800
DOI: 10.1055/s-1991-20800
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Hydroesterification of 6-Methoxy-2-naphthylethene
Further Information
Publication History
Publication Date:
07 March 2002 (online)
Palladium-catalyzed hydroesterification (hydroalkoxy-carbonylation) of 6-methoxy-2-naphthylethene was found to proceed under 10 to 60 atm of carbon monoxide in an alcoholcosolvent mixture at 50 °C to 100 °C to afford 2-(6-methoxy-2-naphthyl)propanoate esters with excellent regioselectivity.