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Synthesis 1987; 1987(1): 10-19
DOI: 10.1055/s-1987-27827
review
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Pyrrolizine Chemistry

G. Hall* , J. K. Sugden, M. B. Waghela
  • *School of Pharmacy, Leicester Polytechnic, P.O. Box 143, Leicester, LE1 9BH, United Kingdom
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Publikationsdatum:
20. August 2002 (online)

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This review presents a short survey of methods for the synthesis of pyrrolizine derivatives and of the reactions of pyrrolizines and dihydropyrrolizes. Brief sections on the spectral properties and medicinal applications of the title compounds are also included. 1. Introduction 2. Nomenclature 3. Synthesis of Pyrrolizine Derivatives 4. Reactions of Pyrrolizine and Dihydropyrrolizine Derivatives 5. Medicinal Chemistry 6. Recent Developments (1982-1986)