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Synthesis 2025; 57(21): 3325-3333
DOI: 10.1055/s-0043-1773536
DOI: 10.1055/s-0043-1773536
Paper
Published as part of the Special Topic Dedicated to Prof. Paul Knochel
Photochemical Activation of Ruthenium Complexes Containing Unsymmetrical Unsaturated N-Heterocyclic Carbenes for Olefin Metathesis
Autoren
This work was supported by the Association Nationale de la Recherche et de la Technologie (CIFRE n° 2017/0873, grants to F.K.) and Agence Nationale de la Recherche ‘France Relance’ (fellowship to A.D.V.).
Dedication
Published in honor of Professor Paul Knochel’s 70th birthday.
Abstract
Olefin metathesis is a fundamental transformation in organic chemist’s toolbox. Herein we report a methodological study on a set of bench stable, latent, ruthenium-indenylidene catalysts bearing two unsymmetrical unsaturated N-heterocyclic carbene (NHC) ligands. These complexes are successfully ‘activated’ and applied to ring-closing metathesis (RCM), cross-metathesis (CM), and ring-opening cross metathesis (ROCM) upon light irradiation in the presence of an organic photoactivator. The transformations could be performed at lower catalyst loading (down to 1 mol%) compared to the state-of-the-art photochemical activation methods, providing good yields in shorter reaction time.
Publikationsverlauf
Eingereicht: 11. Februar 2025
Angenommen nach Revision: 19. März 2025
Artikel online veröffentlicht:
16. April 2025
© 2025. Thieme. All rights reserved.
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For previous light-activation of olefin metathesis catalysts, see: