Appl Clin Inform 2020; 11(04): 589-597
DOI: 10.1055/s-0040-1715893
Research Article

Considerations for Designing EHR-Embedded Clinical Decision Support Systems for Antimicrobial Stewardship in Pediatric Emergency Departments

Mustafa Ozkaynak
1  College of Nursing, University of Colorado-Denver, Anschutz Medical Campus, Aurora, Colorado, United States
Noel Metcalf
1  College of Nursing, University of Colorado-Denver, Anschutz Medical Campus, Aurora, Colorado, United States
Daniel M. Cohen
2  Division of Emergency Medicine, Nationwide Children's Hospital, Columbus, Ohio, United States
Larissa S. May
3  Department of Emergency Medicine, UC Davis Health, Davis, California, United States
Peter S. Dayan
4  Division of Pediatric Emergency Medicine, Department of Emergency Medicine, Columbia University College of Physicians and Surgeons, New York, New York, United States
Rakesh D. Mistry
5  Department of Pediatrics and Emergency Medicine, Section of Emergency Medicine, School of Medicine, University of Colorado, Anschutz Medical Campus, Aurora, Colorado, United States
› Author Affiliations
Funding This study was supported by National Institute of Allergy and Infectious Diseases (NIAID) under award number R21AI139839 (principal investigator: R.D.M.).


Objective This study was aimed to explore the intersection between organizational environment, workflow, and technology in pediatric emergency departments (EDs) and how these factors impact antibiotic prescribing decisions.

Methods Semistructured interviews with 17 providers (1 fellow and 16 attending faculty), and observations of 21 providers (1 physician assistant, 5 residents, 3 fellows, and 12 attendings) were conducted at three EDs in the United States. We analyzed interview transcripts and observation notes using thematic analysis.

Results Seven themes relating to antibiotic prescribing decisions emerged as follows: (1) professional judgement, (2) cognition as a critical individual resource, (3) decision support as a critical organizational resource, (4) patient management with imperfect information, (5) information-seeking as a primary task, (6) time management, and (7) broad process boundaries of antibiotic prescribing.

Discussion The emerging interrelated themes identified in this study can be used as a blueprint to design, implement, and evaluate clinical decision support (CDS) systems that support antibiotic prescribing in EDs. The process boundaries of antibiotic prescribing are broader than the current boundaries covered by existing CDS systems. Incongruities between process boundaries and CDS can under-support clinicians and lead to suboptimal decisions. We identified two incongruities: (1) the lack of acknowledgment that the process boundaries go beyond the physical boundaries of the ED and (2) the lack of integration of information sources (e.g., accessibility to prior cultures on an individual patient outside of the organization).

Conclusion Significant opportunities exist to improve appropriateness of antibiotic prescribing by considering process boundaries in the design, implementation, and evaluation of CDS systems.

Protection of Human and Animal Subjects

The study protocol was approved by the Colorado Multiple Institutional Review Board.

Supplementary Material

Publication History

Received: 24 March 2020

Accepted: 21 July 2020

Publication Date:
09 September 2020 (online)

Georg Thieme Verlag KG
Stuttgart · New York