Synthesis 2021; 53(07): 1200-1212
DOI: 10.1055/s-0040-1706001
short review

The Synthesis of Conjugated Bis-Aryl Vinyl Substrates and Their Photoelectrocyclization Reactions towards Phenanthrene Derivatives

Xuchen Zhao
,
The authors would like to thank the National Science Foundation (CHE 1465113) and the National Institutes of Health (GM132531-02) for their support of this work.


Abstract

The photoelectrocyclization of conjugated vinyl biaryls has proven to be a valuable and efficient strategy for generating phenanthrene derivatives. Contained in this review is an overview of the mechanism for the transformation and a discussion of the reaction scope with a focus on the electrocyclization itself, rearomatization, and the application of the reaction in natural product synthesis.

1 Introduction

2 The Synthesis of Conjugated Vinyl Biaryls

3 Mechanistic Studies

4 Substrate Scope

5 Applications

6 Conclusions



Publication History

Received: 27 October 2020

Accepted after revision: 24 November 2020

Publication Date:
11 January 2021 (online)

© 2021. Thieme. All rights reserved

Georg Thieme Verlag KG
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