Abstract
Isatin derivatives are widely used in organic synthesis, in medicinal chemistry and
in the chemistry of materials. This report summarizes modern trends in the synthesis
of substituted indolin-2,3-diones covering the literature from 2007 to 2017. Studies
on the influence of the structure of substituents in the initial substrates on the
formation of the heterocyclic isatin system and the yields of the target compounds
are also discussed.
1 Introduction
2 Oxidation of Indole Derivatives
3 Cyclization of o-Aminoacetophenones
4 Cyclization of N-Acylanilines
5 Miscellaneous
6 Conclusion
Key words
isatins - heterocyclization - indoles - C–C bond formation - catalysis
