2-(Aminomethyl)-3-arylindoles from 3-(o-Trifluoroacetamidoaryl)-1-propargylic Alcohols, Aryl Halides, and Amines: A Domino Palladium-Catalyzed Three-Component Approach
Received: 13 March 2017
Accepted after revision: 04 April 2017
28 April 2017 (eFirst)
Published as part of the Special Topic Modern Cyclization Strategies in Synthesis
A simple, straightforward palladium-catalyzed approach to 2-(aminomethyl)-3-arylindoles from 3-(o-trifluoroacetamidoaryl)-1-propargylic alcohols, amines, and aryl iodides has been developed.