A Three-Step Protocol towards N-8-(2,2-Dimethoxyethyl)-2-methylsulfanylpyrido[2,3-d]pyrimidin-7-one

Abstract

An efficient high-yielding three-step synthesis of N-8-(2,2-dimethoxyethyl)-2-methylsulfanylpyrido[2,3-d]pyrimidin-7-one is reported. The route utilises a Heck coupling as the key step.

Key words

selective - Heck - cyclisation - pyrido[2,3-d]pyrimidin-7-one - Pd(Ph₃)₄

• References

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