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Synthesis 2016; 48(11): 1616-1621
DOI: 10.1055/s-0035-1561399
DOI: 10.1055/s-0035-1561399
feature
Pd-Catalyzed Homo Cross-Dehydrogenative Coupling of 2-Arylpyridines by Using I2 as the Sole Oxidant
Further Information
Publication History
Received: 11 January 2016
Accepted after revision: 12 February 2016
Publication Date:
10 March 2016 (online)
Abstract
A palladium-catalyzed homo cross-dehydrogenative coupling (CDC) of 2-arylpyridines via C–H activation is described. This reaction employs I2 as the sole oxidant without any other additives, which complements the hypervalent iodine chemistry, such as of phenyliodonium diacetate (PIDA) or IOAc, in C–H activation research field. A tentative mechanism involving a Pd(II)–Pd(IV) catalytic cycle is proposed to rationalize this homo CDC reaction.
Supporting Information
- Supporting information for this article is available online at http://dx.doi.org/10.1055/s-0035-1561399.
- Supporting Information
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