Synthesis 2014; 46(17): 2293-2296
DOI: 10.1055/s-0034-1378207
special topic
© Georg Thieme Verlag Stuttgart · New York

Copper-Free Cleavage-Sonogashira Conjugation of Silylacetylene Immobilized Peptides

Martin Strack
Inorganic Chemistry 1, Bioinorganic Chemistry, Department of Chemistry and Biochemistry, Ruhr University Bochum, Universitätsstr. 150, 44780 Bochum, Germany   Email: h.b.albada@gmail.com
,
Nils Metzler-Nolte
Inorganic Chemistry 1, Bioinorganic Chemistry, Department of Chemistry and Biochemistry, Ruhr University Bochum, Universitätsstr. 150, 44780 Bochum, Germany   Email: h.b.albada@gmail.com
,
H. Bauke Albada*
Inorganic Chemistry 1, Bioinorganic Chemistry, Department of Chemistry and Biochemistry, Ruhr University Bochum, Universitätsstr. 150, 44780 Bochum, Germany   Email: h.b.albada@gmail.com
› Author Affiliations
Further Information

Publication History

Received: 28 February 2014

Accepted after revision: 05 May 2014

Publication Date:
24 June 2014 (online)

Abstract

A one-pot copper-free fluoride-initiated method for the Sonogashira cross-coupling of SAM2-immobilized peptides is described.

Supporting Information

 
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