Synthesis 2012; 44(20): 3209-3215
DOI: 10.1055/s-0032-1316759
paper
© Georg Thieme Verlag Stuttgart · New York

Development of Tartaric Acid Derived Hydrogen-Bond Donors

Markus Boris Laubera, Roland Fröhlichb, Jan Paradies*a
  • aInstitute for Organic Chemistry, Karlsruhe Institute of Technology, Fritz-Haber-Weg 6, 76131 Karlsruhe, Germany, Fax: +49(721)60848581   Email: jan.paradies@kit.edu
  • bInstitute of Organic Chemistry, University of Münster, Corrensstrasse 40, 48149 Münster, Germany
Further Information

Publication History

Received: 24 May 2012

Accepted after revision: 29 June 2012

Publication Date:
03 September 2012 (eFirst)

Abstract

A flexible synthesis of bifunctional thiourea derivatives based on the TADDOL framework is described. Hydroxy as well as primary, secondary, and tertiary amino-substituted bifunctional hydrogen­-bond donors were synthesized.

 
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