Ligand-Free Nickel-Catalyzed Conversion of Aldoximes into Nitriles
14 July 2011 (eFirst)
Catalytic dehydration of aldoximes can be performed efficiently with NiCl2 in acetonitrile under neutral and mild conditions. Under these conditions, various functionalized aldoximes produce the corresponding nitriles in good to excellent yields.
aldehydes - nickel - nitrile - catalysis - elimination