Ligand-Free Nickel-Catalyzed
Conversion of Aldoximes into Nitriles

Yen-Ting Li; Bei-Sih Liao; Hsin-Pei Chen; Shiuh-Tzung Liu

doi:10.1055/s-0030-1260119

PAPER

Ligand-Free Nickel-Catalyzed Conversion of Aldoximes into Nitriles

Yen-Ting Li^a, Bei-Sih Liao^a, Hsin-Pei Chen*^b, Shiuh-Tzung Liu*^a
^a Department of Chemistry, National Taiwan University, Taipei 106, Taiwan
Fax: +886(2)23636359; e-Mail: stliu@ntu.edu.tw;
^b Department of Mechanical Engineering, Tungnan University, Shenkeng Dist., New Taipei City 222, Taiwan

Abstract

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Abstract

Catalytic dehydration of aldoximes can be performed efficiently with NiCl₂ in acetonitrile under neutral and mild conditions. Under these conditions, various functionalized aldoximes produce the corresponding nitriles in good to excellent yields.

Key words

aldehydes - nickel - nitrile - catalysis - elimination

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References

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