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Synthesis 2011(9): 1465-1471
DOI: 10.1055/s-0030-1259970
DOI: 10.1055/s-0030-1259970
PAPER
© Georg Thieme Verlag
Stuttgart ˙ New York
Reaction of Ethyl 5-Acetyl-3,4-dihydropyridine-1(2H)-carboxylate with 1,3-N,N-Bis-nucleophiles: A Facile Access to Novel Pyrimidine Derivatives
Weitere Informationen
Received
27 January 2011
Publikationsdatum:
24. März 2011 (online)
Publikationsverlauf
Publikationsdatum:
24. März 2011 (online)
Abstract
Reaction of ethyl 5-acetyl-3,4-dihydropyridine-1(2H)-carboxylate with diverse 1,3-N,N-bis-nucleophiles results in the regioselective formation of the correspondingly substituted pyrimidines in good yields.
Key words
pyrimidines - amidines - amino heterocycles - tetrahydropyridine
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