Synthesis 2010(11): 1781-1792
DOI: 10.1055/s-0029-1219760
DOI: 10.1055/s-0029-1219760
PAPER
© Georg Thieme Verlag
Stuttgart ˙ New YorkRegioselective Reaction of Ethyl 5-Acetyl-3,4-dihydropyridine-1(2H)-carboxylate with Hydrazines: A Facile Approach to New Pyrazole Derivatives
Further Information
Received
26 February 2010
Publication Date:
06 April 2010 (online)
Publication History
Publication Date:
06 April 2010 (online)

Abstract
The reaction of ethyl 5-acetyl-3,4-dihydropyridine-1(2H)-carboxylate with diverse aliphatic as well as aromatic monosubstituted hydrazines resulted in the regioselective formation of N-substituted 3-methylpyrazoles.
Key words
pyrazole - hydrazine - tetrahydropyridine - regioselectivity
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