Asymmetric Cyanosilylation with Supported Cu(II) Salen Complexes

G. Rajagopal; S. Selvaraj; K. Dhahagani

doi:10.1055/s-0030-1258916

Subscribe to RSS

Please copy the URL and add it into your RSS Feed Reader.

https://www.thieme-connect.de/rss/thieme/en/10.1055-s-00000131.xml

Share / Bookmark

Facebook X Linkedin Weibo

Download PDF

Synfacts 2010(12): 1436-1436
DOI: 10.1055/s-0030-1258916

Polymer-Supported Synthesis

Asymmetric Cyanosilylation with Supported Cu(II) Salen Complexes

Contributor(s): Yasuhiro Uozumi, Haifeng Zhou
G. Rajagopal*, S. Selvaraj, K. Dhahagani
Government Arts College, Madurai, India

Further Information

Publication History

Publication Date:
22 November 2010 (online)

Permissions and Reprints

Significance

JandaJel-supported Cu(salen) complex 3 catalyzed the asymmetric cyanosilylation of aromatic and heterocyclic ketones 1 with TMSCN in the presence of Ph₃PO to give the corresponding cyanohydrin trimethylsilyl ethers 2 in 83-96% yield with 52-84% ee.