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Synthesis
DOI: 10.1055/a-2675-3935
DOI: 10.1055/a-2675-3935
Paper
Published as part of the Special Topic Dedicated to Prof. Paul Knochel
Iron Catalyst and Blue Light Partnership for Selective Desulfurization of Secondary and Primary Thioamides
Supported by: National Research Agency ANR-22-PESP-0006
Funding Information This work benefited from State aid managed by the National Research Agency under France 2030 with the reference “ANR-22-PESP-0006”. Q.Z. thanks the China Scholarship Council for a PhD fellowship.
Dedication
In honor of Prof. Paul Knochel’s 70th birthday and for his incredible creativity, dynamism, and inspiration.
Abstract
Commercially available iron(0) Fe2(CO)9 precatalyst can promote the selective desulfurization of secondary and primary carboxamides leading to the corresponding secondary amines and nitriles, respectively. The reaction is conducted under hydrosilylation conditions using phenylsilane or diethylsilane and blue LED irradiation (2 × 24 W, 450–460 nm) at ambient conditions.
Keywords
Iron catalysis - Desulfurization - Hydrosilylation; Secondary thioamide - Primary thioamide - Blue lightPublication History
Received: 20 June 2025
Accepted after revision: 03 August 2025
Accepted Manuscript online:
04 August 2025
Article published online:
01 September 2025
© 2025. Thieme. All rights reserved.
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