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DOI: 10.1055/a-2616-9992
Rethinking the Biohazardous Bodily Fluids Alert for Improved Workflow and Safety
Authors
Funding None.

Abstract
Background
Ensuring clinician safety in health care settings is critical, particularly regarding exposure to hazardous drugs and bodily fluids, which can be carcinogenic, teratogenic, genotoxic, or cause organ toxicity at low doses. At SickKids a safety issue arose when a clinician was unknowingly exposed to hazardous bodily fluids due to inadequate communication of a patient's hazardous medication status.
Objectives
This clinical decision support (CDS) redesign aimed to reduce alert fatigue while ensuring timely team awareness to minimize hazardous bodily fluid exposure risk. This case study aims to explore how redesigning a CDS system addressed the dual challenge of maintaining safety communication while minimizing alert fatigue and improving workflow integration.
Methods
In 2018, a biohazardous bodily fluids alert was introduced within the hospital's electronic patient record (EPR) to raise awareness. However, its frequent and disruptive nature resulted in a 0% alert action rate and 89 unactionable clinician hours over a 90-day period. Feedback collected over 42 months revealed clinician frustration and desensitization due to the alert's timing and frequency. Using a human-centered design approach, the alert was redesigned from an interruptive pop-up to a passive notification embedded within the patient's storyboard.
Results
The redesigned alert allowed clinicians to review hazardous status information without immediate interruptions, reducing workflow disruption while maintaining its critical safety function. This approach effectively balanced safety communication with clinicians' need for efficient workflows, addressing the root cause of alert fatigue.
Conclusion
This case study highlights the importance of ongoing CDS evaluation and redesign to enhance clinician safety, minimize alert fatigue, and improve workflow integration. Future evaluations will assess the redesign's effect on personal protective equipment compliance and clinician burnout.
Keywords
alert fatigue - human-centered design - clinical decision support - usability - hazardous drug safetyProtection of Human and Animal Subjects
No human subjects were involved in this project.
Publication History
Received: 02 January 2025
Accepted: 20 May 2025
Article published online:
03 October 2025
© 2025. Thieme. All rights reserved.
Georg Thieme Verlag KG
Oswald-Hesse-Straße 50, 70469 Stuttgart, Germany
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