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Synthesis 2024; 56(12): 1843-1850
DOI: 10.1055/a-2232-8633
DOI: 10.1055/a-2232-8633
short review
Mechanism of the Mitsunobu Reaction: An Ongoing Mystery
We thank the National Institutes of Health (NIH; grant R01GM071779) for financial support.
Abstract
The Mitsunobu reaction is one the most widely known reactions in the organic chemistry canon. Despite its fame, some aspects of the mechanism remain poorly understood, 55 years after its initial discovery. This short review collates the findings of several publications focused on the mechanism of the Mitsunobu reaction, highlighting both the current state of knowledge and the remaining missing pieces.
1 Introduction
2 Mechanism Overview
3 Mechanistic Investigations
4 Conclusion
Publikationsverlauf
Eingereicht: 14. November 2023
Angenommen nach Revision: 19. Dezember 2023
Accepted Manuscript online:
19. Dezember 2023
Artikel online veröffentlicht:
24. Januar 2024
© 2023. Thieme. All rights reserved
Georg Thieme Verlag KG
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