Synlett 2024; 35(11): 1301-1305
DOI: 10.1055/a-2214-5397
cluster
Japan/Netherlands Gratama Workshop

Synthesis of an Alternating Polycation with the Dense 1,2,3-Triazole Backbone

Tomoki Omae
a   Department of Macromolecular Science, Graduate School of Science, Osaka University, Machikaneyama-cho, Toyonaka, Osaka 560-0043, Japan
,
Masaki Nakahata
a   Department of Macromolecular Science, Graduate School of Science, Osaka University, Machikaneyama-cho, Toyonaka, Osaka 560-0043, Japan
,
Yuri Kamon
b   Administration Department, Graduate School of Science, Osaka University, Machikaneyama-cho, Toyonaka, Osaka 560-0043, Japan
,
a   Department of Macromolecular Science, Graduate School of Science, Osaka University, Machikaneyama-cho, Toyonaka, Osaka 560-0043, Japan
› Author Affiliations


Abstract

Polycations are an important class of water-soluble polymers because they form polyion complexes with DNA. Thus, the synthesis of polycations with controlled monomer sequences will be of increasing importance for the formation of well-defined polyion complexes. In this study, cationic homopolymer and alternating copolymer with the dense triazole backbone were synthesized by copper(I)-catalyzed azide–alkyne cycloaddition polymerization. The polycations obtained were characterized by potentiometric and turbidimetric titrations, and by complex formation with poly(acrylic acid).

Supporting Information



Publication History

Received: 26 October 2023

Accepted after revision: 20 November 2023

Accepted Manuscript online:
20 November 2023

Article published online:
08 January 2024

© 2023. Thieme. All rights reserved

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany