Abstract
Visible-light-mediated novel metal-free, oxidant-free phosphoric acid-catalyzed method
for the synthesis of 2-selanyl NHCbz-tryptamines/3-subtituted indoles is presented.
This direct C-2 selenation strategy, with environmental benign conditions by reaction
of tryptamines/3-substituted indoles and diaryl/dialkyl selenides, allows access to
a wide range of 2-aryl/alkylselanyl NHCbz-tryptamines/3-substituted indoles. An experimental
investigation using UV/Vis, cyclic voltammetry, and controlled experiments sheds light
on the plausible mechanism.
Key words
visible light - 3-methylindole - tryptamine - diphenyl diselenide - diphenyl phosphate
