Synthesis 2024; 56(04): 567-572
DOI: 10.1055/a-2076-9792
DOI: 10.1055/a-2076-9792
special topic
Synthetic Development of Key Intermediates and Active Pharmaceutical Ingredients (APIs)
Biocatalytic Synthesis of Chiral Benzylic Alcohols via Enantioselective Hydroxylation by a Self-Sufficient Cytochrome P450 from Deinococcus gobiensis
Hai-Bo Cui
a
Key Laboratory of Biocatalysis & Chiral Drug Synthesis of Guizhou Province, Generic
Drug Research Center of Guizhou Province, Green Pharmaceuticals Engineering Research
Center of Guizhou Province, School of Pharmacy, Zunyi Medical University, Zunyi, 563000, P. R. of China
b
Key Laboratory of Basic Pharmacology of Ministry of Education, and Joint International
Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, Zunyi, 563000, P. R. of China
,
Ting Ma
a
Key Laboratory of Biocatalysis & Chiral Drug Synthesis of Guizhou Province, Generic
Drug Research Center of Guizhou Province, Green Pharmaceuticals Engineering Research
Center of Guizhou Province, School of Pharmacy, Zunyi Medical University, Zunyi, 563000, P. R. of China
b
Key Laboratory of Basic Pharmacology of Ministry of Education, and Joint International
Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, Zunyi, 563000, P. R. of China
,
Ru-Yue Zhang
a
Key Laboratory of Biocatalysis & Chiral Drug Synthesis of Guizhou Province, Generic
Drug Research Center of Guizhou Province, Green Pharmaceuticals Engineering Research
Center of Guizhou Province, School of Pharmacy, Zunyi Medical University, Zunyi, 563000, P. R. of China
b
Key Laboratory of Basic Pharmacology of Ministry of Education, and Joint International
Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, Zunyi, 563000, P. R. of China
,
Jing Shan
a
Key Laboratory of Biocatalysis & Chiral Drug Synthesis of Guizhou Province, Generic
Drug Research Center of Guizhou Province, Green Pharmaceuticals Engineering Research
Center of Guizhou Province, School of Pharmacy, Zunyi Medical University, Zunyi, 563000, P. R. of China
b
Key Laboratory of Basic Pharmacology of Ministry of Education, and Joint International
Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, Zunyi, 563000, P. R. of China
,
Zhong-Qiang Wang
a
Key Laboratory of Biocatalysis & Chiral Drug Synthesis of Guizhou Province, Generic
Drug Research Center of Guizhou Province, Green Pharmaceuticals Engineering Research
Center of Guizhou Province, School of Pharmacy, Zunyi Medical University, Zunyi, 563000, P. R. of China
b
Key Laboratory of Basic Pharmacology of Ministry of Education, and Joint International
Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, Zunyi, 563000, P. R. of China
,
Mei Bai
a
Key Laboratory of Biocatalysis & Chiral Drug Synthesis of Guizhou Province, Generic
Drug Research Center of Guizhou Province, Green Pharmaceuticals Engineering Research
Center of Guizhou Province, School of Pharmacy, Zunyi Medical University, Zunyi, 563000, P. R. of China
b
Key Laboratory of Basic Pharmacology of Ministry of Education, and Joint International
Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, Zunyi, 563000, P. R. of China
,
Yong-Zheng Chen∗
a
Key Laboratory of Biocatalysis & Chiral Drug Synthesis of Guizhou Province, Generic
Drug Research Center of Guizhou Province, Green Pharmaceuticals Engineering Research
Center of Guizhou Province, School of Pharmacy, Zunyi Medical University, Zunyi, 563000, P. R. of China
b
Key Laboratory of Basic Pharmacology of Ministry of Education, and Joint International
Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, Zunyi, 563000, P. R. of China
› Author Affiliations