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Synlett 2022; 33(08): 721-727
DOI: 10.1055/a-1696-4418
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Reactions of Sulfoxides with Benzynes

Caiwen Wan
a   School of Chemistry and Chemical Engineering, Chongqing University, Chongqing 401331, P. R. of China
,
Jiarong Shi  ∗
a   School of Chemistry and Chemical Engineering, Chongqing University, Chongqing 401331, P. R. of China
,
Yang Li∗
a   School of Chemistry and Chemical Engineering, Chongqing University, Chongqing 401331, P. R. of China
b   College of Chemistry, Jilin University, Changchun 130012, P. R. of China
› Author AffiliationsThe authors gratefully acknowledge the support of this work provided by the Basic and Frontier Research Project of Chongqing (cstc2019jcyj-bshX0021) and NSFC (21901025, 21971028, 21772017).
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Abstract

Sulfoxides are important organic synthons that have been used in a variety of transformations. In this account, we focus on advances in the reaction of sulfoxides with benzynes, which can be divided into two types: benzyne ortho-difunctionalization and benzyne multifunctionalization.

1 Introduction

2 Benzyne ortho-Difunctionalization

3 Benzyne Multifunctionalization

4 Conclusion

Key words

sulfoxides - benzynes - difunctionalization - multifunctionalization - cascade reaction


Publication History

Received: 29 October 2021

Accepted after revision: 13 November 2021

Accepted Manuscript online:
13 November 2021

Article published online:
21 December 2021

© 2021. Thieme. All rights reserved

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

 

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