Synthesis of Ruthenium Catalysts with a Chiral Arene Ligand Derived from Natural Camphor

Abstract

A ruthenium complex with a chiral arene ligand [(camphor–arene)RuCl₂]₂ was synthesized by the reaction of RuCl₃·nH₂O with a chiral diene which was obtained from natural camphor in three steps. This complex catalyzed the asymmetric hydrogenation of acetophenone (64–85% ee), but decomposed in catalytic reactions involving C–H activation of 2-phenylpyridine or benzoic acid derivatives.

Key words

ruthenium - arene complexes - asymmetric catalysis - camphor - C–H activation

Publication History

Received: 28 September 2021

Accepted after revision: 13 October 2021

Accepted Manuscript online:
13 October 2021

Article published online:
22 November 2021

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