Download PDF
Synlett 1996; 1996(6): 573-575
DOI: 10.1055/s-1996-5480
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Selective Pd(0)-Catalyzed Arylations with New Electrophilic or Nucleophilic Multi-Coupling Reagents

Mario Rottländer, Nick Palmer, Paul Knochel*
  • *Fachbereich Chemie der Philipps-Universität Marburg, D-35032 Marburg (Germany), Fax: 49-6421-282189, e-mail: Knochel@ps1515.chemie.uni-marburg.de
Further Information

Publication History

Publication Date:
31 December 2000 (online)

 PDF Download  Permissions and Reprints All articles of this category

Reaction conditions have been developed allowing the selective coupling of arylzinc reagents with aryl iodides at rt (Pd(dba)2 cat, tfp cat) and aryl triflates at 65 °C, (Pd(dba)2 cat, dppf cat). Thus, o, m, p-iodoaryl triflates could be used as efficient multi-coupling reagents and selectively reacted with two different organozincs leading to various terphenyls. A new synthesis of diarylzincs starting from an arylsilane has also been found. After a successive silicon-boron and boron-zinc exchange, the diarylzinc is obtained in good yield and used as a nucleophilic multi-coupling reagent.

palladium-catalyzed cross-coupling - polyfunctional biphenyls and terphenyls