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Synlett 1996; 1996(6): 573-575
DOI: 10.1055/s-1996-5480
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Selective Pd(0)-Catalyzed Arylations with New Electrophilic or Nucleophilic Multi-Coupling Reagents

Mario Rottländer, Nick Palmer, Paul Knochel*
  • *Fachbereich Chemie der Philipps-Universität Marburg, D-35032 Marburg (Germany), Fax: 49-6421-282189, e-mail: Knochel@ps1515.chemie.uni-marburg.de
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Publication History

Publication Date:
31 December 2000 (online)

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Reaction conditions have been developed allowing the selective coupling of arylzinc reagents with aryl iodides at rt (Pd(dba)2 cat, tfp cat) and aryl triflates at 65 °C, (Pd(dba)2 cat, dppf cat). Thus, o, m, p-iodoaryl triflates could be used as efficient multi-coupling reagents and selectively reacted with two different organozincs leading to various terphenyls. A new synthesis of diarylzincs starting from an arylsilane has also been found. After a successive silicon-boron and boron-zinc exchange, the diarylzinc is obtained in good yield and used as a nucleophilic multi-coupling reagent.

palladium-catalyzed cross-coupling - polyfunctional biphenyls and terphenyls

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