First Triphenylphosphine Promoted Reduction of Maleimides to Succinimides

Abstract

Triphenylphosphine (TPP) in refluxing methanol effectively reduces maleimides 1a-g to the corresponding succinimides 2a-g in good yields. It was observed that some maleimides obtained from aromatic halogen compounds 1h-j were transformed into the corresponding succinamic acid methyl esters 3a-c by this reaction.

Key words

triphenylphosphine - reductions - maleimides - succinimides - succinamic acid methyl esters

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11

Dichiaro, J. V.;, Bate, R. A.; Johnron, W.; Keller, R. A. 4 ^th Chromatogr. Electrophor. Symp. Int.,Tuscon, Arizona 1966.