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Synthesis 2002(11): 1541-1545
DOI: 10.1055/s-2002-33336
DOI: 10.1055/s-2002-33336
PAPER
© Georg Thieme Verlag Stuttgart · New York
The Oxa-Pictet-Spengler Reaction of 1-(3-Furyl)alkan-2-ols
Further Information
Received
11 March 2002
Publication Date:
23 August 2002 (online)
Publication History
Publication Date:
23 August 2002 (online)
Abstract
The oxa-Pictet-Spengler reaction of 1-(3-furyl)alkan-2-ols with aldehydes catalyzed by p-toluenesulfonic acid gives good yields of the corresponding cis-5,7-disubstituted 4,5-dihydro-7H-furano[2,3-c]pyrans.
Key words
oxa-Pictet-Spengler reaction - furans - cyclizations - Lewis acids - ene reactions
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