An Efficient Preparation of 6-Alkoxy-substituted Benzocyclobutenones

Abstract

A short, efficient route to 3-alkoxybenzynes has been developed, starting from readily available compounds. This has enabled rapid access to 6-alkoxybenzocyclobutenones, which are valuable synthetic intermediates.

Key words

benzynes - benzocyclobutenone derivatives - [2+2] cycloadditions - metalations - protecting groups

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