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Synthesis 2000; 2000(1): 123-126
DOI: 10.1055/s-2000-6233
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The Michael Reaction of N-Cinnamoylazoles with Phenols. A Simple Synthesis of 4-Arylchroman-2-ones and 1-Arylbenzo[f]chroman-3-ones

Giovanna Speranza* , Carlo F. Morelli, Paolo Manitto
  • *Dipartimento di Chimica Organica e Industriale, Università di Milano and Centro di Studio per le Sostanze Organiche Naturali, CNR, via Venezian 21, I-20133 Milano, Italy; Fax +39 (2) 2 36 43 69; E-mail: giovanna.speranza@unimi.it
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Publication Date:
31 December 2000 (online)

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4-Arylchroman-2-ones 3 and 1-arylbenzo[f]chroman-3-ones 6 have been prepared in moderate to good yields by reaction of dihydric or trihydric phenols with p-substituted N-cinnamoylazoles in dichloromethane under reflux in the presence of DBU.

Michael reaction - N-cinnamoylazoles - 4-arylchroman-2-ones - 1-arylbenzo[f]chroman-3-ones - phenols

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