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Synthesis 1999; 1999(4): 583-585
DOI: 10.1055/s-1999-3427
short paper
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Preparation of Enantioenriched α-Bromo Acids Incorporating Diverse Functionality

Andrew J. Souers* , Stephan Schürer, Heemun Kwack, Alex A. Virgilio, Jonathan A. Ellman
  • *Department of Chemistry, University of California, Berkeley, CA 94720, USA; Fax +(5 10)6 43 83 69; E-mail: jellman@uclink.berkeley.edu
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Publication Date:
31 December 1999 (online)

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A number of enantioenriched α-bromo acids with diverse side chain functionality have been synthesized in one step from their corresponding protected α-amino acids. Good yields and excellent enantiopurities were observed for all substrates examined.

α-bromo acids - α-amino acids - acid labile side chain protecting groups

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