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Synthesis 1994; 1994(12): 1411-1412
DOI: 10.1055/s-1994-25703
short paper
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Facile Synthesis of Novel Polysubstituted Isobenzofuranones

Reda M. El-Shishtawy* , Koushi Fukunishi
  • *Department of Chemistry and Materials Technology, Kyoto Institute of Technology, Matsugasaki, Sakyo-ku, Kyoto 606, Japan
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Publication Date:
25 April 2002 (online)

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Grignard addition to polysubstituted phthalic anhydride 3 yielded the corresponding hydroxyisobenzofuranones 4, which were reduced by lithium triethylborohydride (Super-Hydride) to afford the novel polysubstituted isobenzofuranones 5 in high yield.

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