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Synthesis 1994; 1994(1): 37-39
DOI: 10.1055/s-1994-25400
short paper
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An Efficient Synthesis of Selectively Functionalized Spermidine

Igor Levchine* , Padinchare Rajan, Marianne Borloo, Willy Bollaert, Achiel Haemers
  • *Department of Pharmaceutical Chemistry, University of Antwerp, Universiteitsplein, 1, B-2610 Antwerpen, Belgium
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Publication Date:
17 September 2002 (online)

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A method is described for the synthesis of selectively protected Boc, Fmoc or Z-spermidine derivatives. The starting spermidine, N8-benzyloxycarbonyl-N 1-tert-butoxycarbonylspermidine is prepared using a reductive amination.

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