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Synthesis 1992; 1992(11): 1145-1150
DOI: 10.1055/s-1992-26323
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Synthese von 3-(Thiazol-4-yl)alanin- und 3-(Selenazol-4-yl)alanin-Derivaten aus Asparaginsäure

Klaus Burger* , Manuel Gold, Horst Neuhauser, Martin Rudolph, Eva Höß
  • *Institut für Organische Chemie der Technischen Universität München Lichtenbergstr. 4, D-8046 Garching, Germany
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Publication Date:
17 September 2002 (online)

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Synthesis of 3-(Thiazol-4-yl)alanine and 3-(Selenazol-4-yl)alanine Derivatives from Aspartic Acid1-4 3-(Thiazol-4-yl)alanine as well as 3-(selenazol-4-yl)alanine and their derivatives can be obtained from aspartic acid, using hexafluoroacetone as protective group, via 2,2-bis(trifluoromethyl)-4-(3-bromo-2-oxopropyl)-1,3- oxazolidin-5-one (3) in a Hantzsch synthesis.

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