PDF herunterladen
Synthesis 1988; 1988(10): 775-777
DOI: 10.1055/s-1988-27704
paper
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Lithium-N-lithiomethyldithiocarbamate: Neue N-Alkylaminomethylanion-Äquivalente

Hubertus Ahlbrecht* , Dieter Kornetzky
  • *Fachbereich Chemie der Universität Gießen, Institut für Organische Chemie, Heinrich-Buff-Ring 58, D-6300 Gießen, Federal Republic of Germany
Weitere Informationen

Publikationsverlauf

Publikationsdatum:
12. September 2002 (online)

  als PDF herunterladen  Lizenzen und Reprints Alle Artikel dieser Rubrik

Lithium N-Lithiomethyldithiocarbamates: New N-Alkylaminomethyl Anion Equivalents A new method for nucleophilic aminomethylation is described. It consists in the in situ conversion of a secondary methylamine to the lithium N-lithiomethyldithiocarbamate, subsequent reaction with one equivalent of an electrophile, and deprotection in a one-pot procedure to give the secondary amine substituted at the methyl group. By reaction with two equivalents of an alkyl iodide, alkyl N,N-dialkyldithiocarbamates, even mixed ones, are available too.

      >