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Synthesis 2003(15): 2358-2362
DOI: 10.1055/s-2003-42398
DOI: 10.1055/s-2003-42398
PAPER
© Georg Thieme Verlag Stuttgart · New York
Expedient Synthesis of Biginelli-Type Dihydropyrimidinones Using α-(Benzotriazolyl)alkyl Urea Derivatives
Further Information
Received
16 June 2003
Publication Date:
29 September 2003 (online)
Publication History
Publication Date:
29 September 2003 (online)
Abstract
Reaction of readily available α-(benzotriazolyl)alkyl urea derivatives (derived from aromatic, heteroaromatic, and aliphatic aldehydes) with β-keto esters resulted in 3,4-dihydropyrimidin-2(1H)-ones in good to excellent yields.
Key words
urea - heterocycles - pyrimidines - condensation - esters - cyclizations
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