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Synfacts 2008(6): 0556-0556  
DOI: 10.1055/s-2008-1072612
Synthesis of Natural Products and Potential Drugs
© Georg Thieme Verlag Stuttgart · New York

Synthesis of (-)-Salviasperanol

Contributor(s): Philip Kocienski, Indu Dager
G. Majetich*, G. Zou, J. Grove
University of Georgia, Athens, USA
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Publication History

Publication Date:
21 May 2008 (online)

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Significance

(-)-Salviasperanol belongs to the family of icetexane diterpenoids. The first total synthesis of (-)-salviasperanol based upon a cyclialkylation strategy is reported here. This asymmetric synthesis, starting from the achiral enynone B, was completed in seven steps.