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Endoscopy 1980; 12(5): 197-199
DOI: 10.1055/s-2007-1021742
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© Georg Thieme Verlag KG Stuttgart · New York

Oesophageal Ulceration Due to Emepronium Bromide

I.G. Barrison, P.N. Trewby, S.P. Kane
  • Departments of Gastroenterology, West Middlesex Hospital, Isleworth, Middlesex and Charing Cross Hospital, London
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Publication History

Publication Date:
17 March 2008 (online)

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Summary

Four cases of oesophageal damage associated with ingestion of the urinary anti-spasmodic agent emepronium bromide are described. All the patients presented with severe retrosternal pain worsened by swallowing food and drink, and in every case fibre-optic endoscopy revealed ulceration of the midoesophagus. Symptoms disappeared rapidly following cessation of emepronium bromide therapy. The means whereby this agent might injure oesophageal mucosa are discussed.

Key words:

Oesophageal ulceration - Emepronium bromide - Odynophagia

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