Am J Perinatol 2004; 21(3): 131-134
DOI: 10.1055/s-2004-823771
Copyright © 2004 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA.

Co-Occurrence of Coarctation of the Aorta and Hypospadias in Smaller Twins in Monochorionic Pregnancies: Two Case Reports

Kazushi Yasuda1 , Shigeru Ohki1 , Masashi Seguchi1
  • 1Department of Pediatrics, Seirei Hamamatsu General Hospital, Hamamatsu, Shizuoka, Japan
Further Information

Publication History

Publication Date:
14 April 2004 (online)

We reconstructed of the aortic arches of two unrelated boys, who were the smaller twin in monochorionic pregnancies, because they had coarctation of the aorta (CoA). They both had hypospadias. The co-twins, the larger twins, had neither CoA nor hypospadias. Although CoA and hypospadias both have been associated separately with monozygotic pregnancy, this is the first report of CoA and hypospadias occurring together. These cases indicate that epigenetic factors such as unbalanced fetal circulation in monochorionic pregnancy may be involved in co-occurrence of CoA and hypospadias.

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Kazushi YasudaM.D. 

Department of Pediatrics, Toyohashi Municipal Hospital

50 Hachiken-nishi, Aotake, Toyohashi

Aichi 441-8570, Japan